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Ginger Root Clinical Studies

Study #1

 

Ginger & Marianne Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial

 

"Results: Forty-five patients in the treatment group and 40 patients in placebo group participated in this study. There was a significant reduce in triglyceride cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), levels of before and after study separately in each group (p0.05). Mean changes in triglyceride and cholesterol levels of ginger group were significantly higher than placebo group (p0.05). Mean reduction in LDL level and increase in high density lipoprotein level of ginger group were higher than the placebo group, but in VLDL level of placebo was higher than ginger(p0.05). Conclusion: The results show that ginger has a significant lipid lowering effect compared to placebo."

 

[Reza Alizadeh-Navaei et al., Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial, Saudi Med J 29(9):1280-1284 (2008). ] 

 

Study #2

 

Effects of ginger supplementation and resistance training on lipid profiles and body composition in obese men

 

"For centuries ginger has been an important ingredient in Chinese, Ayurvedic and Tibb-Unani herbal medicine (Badreldin et al., 2008). Ginger modifies lipid metabolism by inhibiting cellular cholesterol biosynthesis, increasing bile acid biosynthesis to eliminate cholesterol from the body and increasing fecal cholesterol excretion (Matsuda et al., 2009)."

 

[Sirvan Atashak, Effects of ginger supplementation and resistance training on lipid profiles and body composition in obese men, Journal of Medicinal Plants Research Vol. 5(16), pp. 3827-3832, 18 August, 2011.] 

 

Study #3

 

Ginger: A potent root

 

"Ginger preparation, Trikatu, was a potent hypo-lipidemic agent because of its ability to reduce triglycerides and LDL cholesterol and to increase HDL. . . . Ginger has been used in eastern medicine for the treatment of gastrointestinal ailments. The combined treatment of antibiotics and ginger were tested for the control and treatment of Helicobacter pylori infections. The treatment was effective and was shown to inhibit H. pylori with synergistic or additive activity."

 

[Heli J. Roy PhD RD et al., Ginger: A potent root, Pennington Nutrition Series 6 (2007) at http://www.pbrc.edu/division-of-education/pdf/pns/PNS_Ginger.pdf] 

 

Study #4

 

Ginger: Its role in xenobiotic metabolism

 

"Ginger has been used extensively in folklore medicine to treat common ailments. Now scientific evidences in favour of some of these beneficial properties are emerging which would support their consumption and use to ameliorate certain disorders. Observations from studies on animals suggest that ginger has the ability to stimulate protective enzymes involved in xenobiotic metabolism."

 

[Kalpagam Polasa and K. Nirmala, Ginger: Its role in xenobiotic metabolism, Indian Council of Medical Research Bulletin, June 2003, 33(6):57-63.] 

 

Study #5

 

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research

 

"It has been reported that treatment with a methanolic extract of dried rhizomes of ginger produced a significant reduction in fructose-induced elevation of lipid levels, bodyweight, hyperglycemia and hyperinsulinemia. Treatment with an ethyl acetate extract of ginger did not produce any significant change in either of the last two parameters. However, it produced a significant reduction in elevated lipid levels and body weight."

 

[Badreldin H. Ali et al., Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research, Food and Chemical Toxicology 46 (2008) 409–420.] 

 
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