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Vitamin B6 & B12 Clinical Studies
Effects of multivitamin and mineral supplementation on adiposity, energy expenditure and lipid profiles in obese Chinese women
"Obese individuals are more likely to have either lower blood concentrations or lower bioavailability of minerals and/or vitamins. However, there are limited data on the effects of nutritional supplementation on body weight (BW) control, energy homeostasis and lipid metabolism in obese subjects. . . . A total of 87 subjects completed the study. After 26 weeks, compared with the placebo group, the MMS group had significantly lower BW, BMI, FM, TC and LDL-C, significantly higher REE and HDL-C, as well as a borderline significant trend of lower RQ (P=0.053) and WC (P=0.071)."
[Y Li et al., Effects of multivitamin and mineral supplementation on adiposity, energy expenditure and lipid profiles in obese Chinese women, International Journal of Obesity 34:1070-1077 (June 2010).]
Vitamin B12 Supplementation of the Diet of Healthy Adults
"Weight gain is probably due to appetite stimulation, although this may not account for the entire effect. It has been hypothesized that vitamin B12 plays a role in the transformation of carbohydrate to fat. . . . Vitamin B12 might influence appetite in a favorable direction either by relieving a deficiency state or by exerting a pharmacologic effect upon the utilization of ingested food."
[Gilbert M. Bane MD and William P. Boger MD, Vitamin B12 Supplementation of the Diet of Healthy Adults, The American Journal of Clinical Nutrition, September-October 1953, Vol 1(6):424-429.]